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Imaging That Lasts: Capture More, Damage Less with Our Spinning Disk Confocal

In this webinar, we will explore how the X-Light V3 spinning disk confocal system enables gentle yet high-performance imaging, making extended time-lapse experiments easier and more reliable.

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CrestOptics is a globally leading provider of advanced optical imaging technologies, with a consolidated presence across more than 50 countries. Founded in 2011, we have evolved into a scaled strategic partner for the world’s largest microscopy manufacturers and the most innovative OEMs in life science industry and beyond, expanding our footprint into high-growth sectors like semiconductor metrology and materials science.


Our leadership is driven by an élite in-house R&D engine which leverages a consolidated expertise to deliver best-in-class solutions across two core pillars: OEM Design-In partnerships, developing customized, high-complexity optical modules for leading platforms and as a preferred Industrial Partner, providing branded spinning disk and super-resolution SIM solutions that integrate seamlessly with systems from global leaders.
Our mission is to deliver best-in-class speed and high-contrast imaging, accelerating scientific discovery across research, pharma, and biotech sectors.

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Our Products

DeepSIM
Super resolution microscopy that answers the deep biological questions effortlessly.
DeepSIM is the first super-resolution module that is compatible with any existing upright or inverted microscope with a camera port. It’s as easy to use as a confocal microscope enabling scientists to access deep data from their biological samples.
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X-Light V3
X-Light V3 is the next generation of X-Light spinning disk confocal series. It relies on the cutting-edge technology, advanced optical design approach and engineering solutions developed by CrestOptics to meet the very high-end specifications required by most of the modern fluorescence microscopy applications.
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X-Light V2
  • Upgrade your inverted and upright microscopes
  • Plug-and-play Spinning Disk Box for wide range of patterns
  • Use of custom-designed lenses for high quality fluorescence imaging
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CICERO
YOUR CONFOCAL JOURNEY STARTS HERE
A flexible, compact but full-fledged spinning-disk confocal solution, CICERO makes high-end fluorescence imaging accessible to every laboratory enabling a variety of applications.
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Expert Testimonials
"Compared to other systems, the X-Light V3 spinning disk is exceptionally fast, making it highly effective for volumetric imaging of large 3D tissues. By utilizing its fast time-lapse capabilities, we achieve the crucial temporal resolution needed for highly dynamic functional assays, all while maintaining an excellent field of view."
Prof. Laurence Pelletier, Dr. Johnny Tkach, Tiger Jian, and Reuben Philip
Prof. Laurence Pelletier, Dr. Johnny Tkach, Tiger Jian, and Reuben PhilipLunenfeld-Tanenbaum Research Institute (LTRI) of Sinai Health, Nikon Centre of Excellence, Toronto, Canada
“The X-Light V3’s high-speed, low-phototoxic imaging allows us to visualize dynamic processes and advanced 3D models in real time. This provides unique insights into complex mechanisms which are essential for identifying novel therapeutic strategies.”
Dr. Lia Asteriti, Dr. Giulia Guarguaglini & Dr. Daniela Trisciuoglio
Dr. Lia Asteriti, Dr. Giulia Guarguaglini & Dr. Daniela TrisciuoglioInstitute of Molecular Biology and Pathology, CNR – Imaging Platform, Rome, Italy
"The integrated multimodal approach with X-Light V3 and DeepSIM streamlines data acquisition, improves experimental efficiency, and supports both exploratory imaging and detailed structural investigations within the same session"
Dr. Carolina Chavez & Dr. Alita Soch
Dr. Carolina Chavez & Dr. Alita Soch The Florey – Microscopy Facility, Melbourne, Australia
"The integrated multimodal approach with X-Light V3 and DeepSIM streamlines data acquisition, improves experimental efficiency, and supports both exploratory imaging and detailed structural investigations within the same session"
Dr. Carolina Chavez & Dr. Alita Soch
Dr. Carolina Chavez & Dr. Alita Soch The Florey – Microscopy Facility, Melbourne, Australia
"The versatility of combining Widefield, Spinning Disk, and Super-Resolution in a single system allows us to address a wide variety of research needs without the need for multiple instruments."
Dr. Liz McCarthy
Dr. Liz McCarthyMicroscopy Technical Specialist at Brunel University of London, United Kingdom
"If I must say something about the CICERO Spinning Disk in one word, that word would be EASY. Moreover, for our researchers, its combination of gentleness and speed is a deal breaker, enabling live cell imaging otherwise not possible."
Dr. Pablo Hernández Varas
Dr. Pablo Hernández VarasHead of Bioimaging Core Leuven VIB, Belgium
"DeepSIM design is optimized for speed and ease of operation, allowing us to efficiently achieve high-quality imaging with minimal effort "
Prof. Vladimir Gelfand
Prof. Vladimir Gelfand Professor, Northwestern University Feinberg School of Medicine, Chicago
“The ease of installation, the performance, and the quality of the images acquired immediately appealed to us. With the acquisition of CICERO, we were able to upgrade our acquisition system to a spinning disk confocal at a reasonable cost.”
Dr. Harald Wodrich
Dr. Harald WodrichDirector of research MFP - CNRS, Université de Bordeaux
“We consider the CICERO Spinning Disk Confocal from CrestOptics the easiest route to confocality for enhancing the optical sectioning quality across the Zebrafish Z-stacks. It is very easy to install and operate on our ZEISS Axio Imager Z1 upright microscope.“
Prof. Paula Sampaio
Prof. Paula SampaioHead of the Advanced Light Microscopy Scientific Platform, i3S Porto (Portugal).
"We build up a high-speed multicolor system on the X-Light V3 spinning disk with which we can perform fast live cell imaging of up to 8 channels simultaneously."
Dr. Emmanuel Derivery
Dr. Emmanuel DeriveryMRC Laboratory of Molecular Biology, Cambridge, UK
“The resolution of the CrestOptics systems is a characteristic of great importance for us. In the lab of Prof. Ohba we study the spatial- temporal relation of signal transduction and we need to see small organelles at high-resolution”
Dr. Yoichiro Fujioka
Dr. Yoichiro FujiokaHokkaido University (Tokyo)
"The main advantages of the CrestOptics systems are speed, sensitivity, ease of use, and flexibility. Moreover, CrestOptics products are very cost-effective ways to collect and evaluate intricate biological processes.”
Mr. Michael Moore
Mr. Michael MooreDelaware state University
"We are utilizing the full capabilities of the X-Light V3 Spinning Disk confocal and DeepSIM systems to develop an imaging-based approach for hyperplex spatial-proteomics.”
Dr. Mario Faretta & <br> Dr. Simona Rodighiero
Dr. Mario Faretta &
Dr. Simona RodighieroIEO (Milan)
“The microscope equipped with X-Light V3 represents a very versatile platform, and it is adaptable with excellent results to the multiple applications I work on”
Prof. Nicolas Baeyens
Prof. Nicolas BaeyensUniversité Libre de Bruxelles
“The unique features of the CrestOptics X-Light V3 Spinning Disk confocal unit, such as the easily interchangeable disk unit combined with the large FOV, illumination shaping and uniformity are the key points which convinced us to adopt the system.”
Dr. Nicola Maghelli & <br> Dr. Gaia Pigino
Dr. Nicola Maghelli &
Dr. Gaia Pigino Human Technopole (Milan)
“Facility users appreciate a lot the easy switch from Widefield to Spinning disk modality, giving them the possibility to select the proper imaging according to their application and experimental needs.”
Dr. Sylvie Le Guyader & <br>Dr. Gabriela Imreh
Dr. Sylvie Le Guyader &
Dr. Gabriela ImrehKarolinska Institutet (Stockholm)
“The main goal we wanted to reach was to have a high-throughput spinning disk system and we largely met our needs with the CrestOptics X-Light V3.”
Dr. Tom Lummen
Dr. Tom LummenETH Zurich
Crest Optics 2025 Bioz Rising Star Badge

Visit our Publications page to explore a collection of scientific articles, where our cutting-edge microscopy instruments have been utilized, enabling significant discoveries across various research fields

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